Colestipol hcl granules

1 treatment consisted of colestipol plus niacin. Table 3-3. Biomass of phytoplankton, microphytobenthos, Chara sp, macrophytes and epiphyte algae in the lake Eckarfjrden g CNP m2 or g CNP m3 and g CNP lake.

The proband was a male born in 1961, referred for evaluation to the Lipid Clinic of Hospital Clnic, Barcelona, in 1995 because of hypercholesterolemia. At age 33 he developed effort angina and was admitted for coronary angiography, which revealed 80% occlusion of one coronary vessel. An angioplasty was performed, but angina recurred after eight months. A restenosis was found at repeat angiography and was treated by placement of an intraluminal stent. He practiced non-competitive sports regularly, had never smoked, had a blood pressure of 115 74 mm Hg, and his body mass index was 24.6 Kg m 2. corneal arcus, xanthelasma, or tendon xantomas were obser ved on clinical examination. Serum cholesterol was 9.95 mmol l, HDL cholesterol HDL-C ; 0.98 mmol l, LDL cholesterol LDL-C ; 8.15 mmol L, triglycerides 1.80 mmol l, and lipoprotein a ; 10 mg dl. After 2 months on a Mediterranean-type hypolipidemic diet, the serum LDL-C was reduced by 25% to 6.07 mmol l. Simvastatin treatment 20 mg daily ; was started, resulting in an additional 55% reduction of LDL-C to 3.67 mmol l. Addition of colestipol 10 g daily ; further lowered LDL-C to 2.38 mmol l, and combined simvastatin-colestipol therapy has been continued for the last 3 years. There was a strong family history of hyperlipidemia and coronary heart disease. The proband's mother had severe hypercholesterolemia, but was free of coronary artery or other vascular diseases. One maternal uncle was known to have a lipid phenotype typical of heterozygous FH and had died of myocardial infarction at age 58. The maternal grandparents lived to old age, but the grandmother suffered from cardiac angina since age 60, and she died of myocardial infarction at age 90. Both were of Spanish origin. The proband's mother and his youngest brother also were referred to the Lipid Clinic in 1995 for evaluation of hypercholesterolemia. The mother had bilateral corneal arcus and xanthoma of the Achilles' tendon. She had no non-lipid cardiovascular risk factors, and she already followed a hypolipidemic diet. Her on-diet LDL-C was 7.20 mmol l and was lowered to 3.28 mmol l after treatment with simvastatin 20 mg daily ; , a 54% reduction. The brother had no classical cardiovascular risk factors, but had a LDL-C of 6.40 mmol l. He was advised to follow a hypolipidemic diet and showed an excellent response, with a LDL-C reduction of 35% to 4.16 mmol l. Their plasma lipid lipoproteins levels are shown in Table 1. This study was approved by the Ethics Committee of the Hospital Clnic i Provincial, Barcelona. All the participants gave their informed consent!