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2. Phase II Study of antineoplastons A-10 and AS2-1 in patients with recurrent or refractory WM. Antineoplastons are naturally occurring substances found in urine, and may inhibit the growth of cancer cells. ; Seeking 20 - 40 patients. Patients will receive injections of antineoplastons 6 times a day. Treatment may be repeated for as long as benefit is shown. Patients will be evaluated every 2 months for 1 year, and then every 3 months for 1 year. Contact: Stanislaw R. Burzynski, Burzynski Research Institute, Houston, TX. Telephone: 713 335-5697. [Protocol: BRI-MW-2] Privately funded ; 3. Phase II Pilot Study of rituximab in patients with WM. Monoclonal antibodies such as rituximab can locate cancer cells and deliver tumorkilling substances to them without harming normal cells. Seeking 66 patients. Patients will receive an infusion of rituximab once a week for 4 weeks. Patients will receive follow-up evaluations every 3 months for 2 years, every 6 continued on page 2.
This table lists the drugs and combination products in RED Book scheduled under the Controlled Substances Act of 1970. In each controlled category, products are listed alphabetically by generic name. Each listing includes the name of a leading or representative brand. GENERIC COMPONENTS CATEGORY II Alfentanil HCI Amobarbital Sodium Amphetamine Dextroamphetamine Amphetamine Sulfate Atropine Meperdine Cocaine HCI Codeine Dextroamphetamine Sulfate Dronabinol Fentanyl Citrate Fentanyl Droperidol Glutehimide Hydromorpyhone HCI Hydromorphone Guifenesin Levorphanol Meperidine HCI Meperidine APAP Meperidine Promethazine Methadone HCI Methamphetamine HCI Methylphenidate Morphine Sulfate Opium Opium Alkaloide Opium Belladonna Oxycodone HCI Oxycodone APAP Oxycodone Aspirin Oxymorphone HCI Secobarbital-Amobarbital Secobarbital Phenobarbital Butabarbitral Suffentanil Citrate REPRESENTATIVE BRAND Alfenta Amytal Sodium Biphetamine Amphetamine Sulfate Atropine & Demarol Cocaine HCI Codeine Dexadrine Marinol Duragesic Innovar Glutehimide Dilaudid-HP Dilaudid Cough Syrup Leva-Dromoran Demerol HCI Demerol APAP Mepergan Dolophine HCI Desoxyn Ritalin Infumorph Opium Pantopon B.&O. Supprettes Roxicodone Percodet Percodan Numorphan HCI Tuinal Tribarb Sufenta Use the table for a quick check when a products status is in doubt. But remember, not all scheduled brands are shown here. For a definitive reading, always check the specific product's labeling.
The brain tends to favor dextroamphetamine to l-amp, but many people do well on adderall b c the mixed salts make for a smoother up & down quicker onset, lasting longer.
HABITAT.--Italy; cultivated in all parts of Europe and United States. DESCRIPTION OF DRUG.--Almost globular, about 3 mm. 1 8 in. ; in diameter, slightly pointed at the apex style ; and with the persistent calyx-teeth around the pedicel-scar at the base. The two concave, hemispherical mericarps are closely united at the edge by the woody pericarp; their outer surface is pale yellowish-brown, sometimes purplish-tinted, with five primary ribs merely indicated by wavy, slightly raised lines, and four more prominent secondary ribs. The interior of the fruit is a lenticular cavity. Odor fragrant the odor of the.
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The Department of Defense DOD ; Prostate Cancer Research Program PCRP ; was established in fiscal year 1997 FY97 ; by Appropriations Conference Committee Report No. 104-863, which provided million M ; for research in prostate cancer. As a major funder of extramural prostate cancer research, the PCRP has managed 5M from FY97 to FY04 to fund peer reviewed prostate cancer research. A total of 1, 013 awards have been made through FY03 to promote innovative, multi-institutional, and multidisciplinary research directed toward conquering prostate cancer. The PCRP believes that building critical resources and collaborations, exploring groundbreaking concepts and ideas, training future leaders, and sponsoring clinical research will ultimately lead to the elimination of prostate cancer see the box story on pages IV-7IV-8 for a review of the clinical trials [CTs] supported by the PCRP ; . Appendix B, Table B-2, summarizes the congressional appropriations and the investment strategy executed by the PCRP for FY0304 and dextromethorphan.
Ability to function especially at school. The medications most commonly prescribed for ADHD are called stimulants. These include methylphenidate Ritalin, Metadate, Concerta ; , amphetamine Adderall ; , dextroamphetamine Dexedrine, Dextrostat ; , and pemoline Cylert ; . Because of its potential for serious side effects on the liver, pemoline is not ordinarily used as a first-line therapy for ADHD. Some antidepressants such as bupropion Wellbutrin ; are often used as alternative medications for ADHD for children who do not respond to or tolerate stimulants. Based on clinical experience and medication knowledge, a physician may prescribe to young children a medication that has been approved by the FDA for use in adults or older children. This use of the medication is called "off-label." Most medications prescribed for childhood mental disorders, including many of the newer medications that are proving helpful, are prescribed off-label because only a few of them have been systematically studied for safety and efficacy in children. Medications that have not undergone such testing are dispensed with the statement that "safety and efficacy have not been established in pediatric patients." The FDA has been urging that products be appropriately studied in children and has offered incentives to drug manufacturers to carry out such testing. The National Institutes of Health and the FDA are examining the issue of medication research in children and are developing new research approaches. The use of the other medications described in this booklet is more limited with children than with adults. Therefore, a special list of medications for children, with the ages approved for their use, appears immediately after the general list of medications. Also listed are NIMH publications with more information on the treatment of both children and adults with mental disorders. THE ELDERLY Persons over the age of 65 make up almost 13 percent of the population of the United States, but they receive 30 percent of prescriptions filled. The elderly generally have more medical problems, and many of them are taking medications for more than one of these conditions. In addition, they tend to be more sensitive to medications. Even healthy older people eliminate some medications from the body more slowly than younger persons and therefore require a lower or less frequent dosage to maintain an effective level of medication. The elderly are also more likely to take too much of a medication accidentally because they forget that they have taken a dose and take another one. The use of a 7-day pill-box, as described earlier in this brochure, can be especially helpful for an elderly person. The elderly and those close to them--friends, relatives, caretakers--need to pay special attention and watch for adverse negative ; physical and psychological responses to medication. Because they often take more medications--not only those prescribed but also over-the-counter preparations and home, folk, or herbal remedies--the possibility of adverse drug interactions is high.
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In addition to the 33 50 chemicals, Bristol-Myers Squibb is obligated to report releases of 33 other SARA 313 chemicals. For most of these chemicals, we released trace amounts. The chart below summarizes our releases for the top 10 chemicals released during 1992, 1993, and the baseline year 1988. As and diamox.
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The most commonly prescribed agent for this is methylphenidate. The recently released once-daily forms are dosed in the morning and enhance compliance and decrease the risk of diversion for school age children. Mixed salts amphetamines Adderall, Adderall XR ; provide an alternative for patients who cannot tolerate methylphenidate. Added to PDL: Focalin, dextroamphetamine generics only ; , methylphenidate generics only ; , methylphenidate ER generics only ; , Concerta, Metadate CD, Methylin ER.
HbA1c glycosylated hemoglobin A1c; FPG fasting plasma glucose * Values obtained from the US FDA package insert. * Reduction in patients who were inadequately controlled on metformin alone. Note: The values listed in the table above are not from direct comparative trials, and therefore are subjected to the limitations associated with this approach. Table adapted from Luna B, et al. Fam Physician. 2001; 63: 1747-56 and diflunisal.
| Amphetamine dextroamphetamine extended-release capsulesChronic non-communicable diseases constitute the major burdens of illness and disability in all countries of the world apart from sub-Saharan Africa, " agreed Stig Pramming, Executive Director of Oxford Health Alliance. "Inaction is costing millions of premature deaths throughout the world and will offset the gains from a decreasing burden of infectious diseases." The economic costs are also substantial. The group estimates that during the next decade, China, India, and the UK will lose US8 billion, US7 billion, and US billion, respectively, as a result of heart disease, stroke, and diabetes. The Alliance consulted 155 diverse stakeholders from 50 countries to identify their priorities, and then refined and ranked these over several rounds of discussion to produce the top 20 list. "The integration of science, technology, policy and social sciences makes the Grand Challenges in [chronic non-communicable diseases] a particularly comprehensive -- if demanding -- blueprint for change, " they say. Many of the challenges relate to policy interventions, rather than basic scientific research. Raising public awareness; enhancing economic, legal, and environmental policies; modifying risk factors; engaging business and community; mitigating the health impacts of poverty and urbanisation; and re-orientating health systems to deal with chronic diseases as well as infectious ones must all be addressed the list suggests. The Grand Challenges Global Partnership has now been set up by the Oxford Health Alliance, UK Medical Research Council, the Canadian Institutes of Health Research, the Indian Council of Medical Research, and the US National Institutes of Health. The Partnership aims to provide co-ordination among all the agencies that should be involved, monitor progress, and advocate for the adoption of the challenges and goals.
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About the ability of foster care to achieve desired outcomes Barbell & Wright 1999 ; has stretched traditional boundaries and opened the way for reform efforts, a number of which have emerged from the United States. In the early 1990s, New York State and New York City launched the Home Rebuilders project to test major reform of the foster care system in New York City Westat Inc. 1998 ; . Essentially, this project tested the effect of capitation payments a flat amount of money for a 3 year period ; , a concept borrowed from managed care. It was anticipated that use of this concept would remove disincentives for reunifying families resulting from traditional per diem payment payment for each day a child is in a foster care placement ; . It was expected that permanency would be achieved earlier due to intensified discharge planning and after care services Westat Inc. 1998 ; . Evaluation of this project concluded that fiscal incentives are unlikely to be a catalyst for major reform in out of home care, although some reduction in the length of out of home placements was evident Mordock 1998 ; . Despite these findings, it has been predicted that the per diem funding system will disappear from out of home care in the United States eventually, even though concerns remain that this could encourage premature discharge from care Mordock 1998 ; . The Annie E. Casey Foundation has promoted the Family to Family initiative in the United States. Family to Family aims to rebuild foster care as a familycentred process where professionals and foster parents are partners with parents in rebuilding their families Omang & Bonk 1999; The Family to Family Evaluation Team 1997 ; . Family to Family reconceptualizes foster care as a bridge, in keeping with the move away from `child rescue', using foster families and local communities to create enduring supportive environments for families Omang & Bonk 1999; The Annie E. Casey Foundation 2000 ; . This allows everyone involved in caring for a child to have a continuing relationship with them during and after placement, to augment the child's family, not to destroy or replace it. Seventeen tools designed to preserve families, reduce the length of time in foster care, and promote sustained reunification, represent new ways of actually doing the work Omang & Bonk 1999; The Annie E. Casey Foundation 2000 ; . Recent evaluation indicates that Family to Family has engineered some key changes to attitudes and frontline foster care practice in the United States, which may help to achieve the desired outcomes over time The Family to Family Evaluation Team 1997 ; . The significance of the Family to Family reform activity is in how it locates foster care within a child's family and community network. Family to Family seeks to create more permeable boundaries for foster care, to position foster care as a service that does not stand alone but in conjunction with other services, the family and the community, provides support to a child and their family during and after out of home placement. Recent use of 'shared family care' approaches is consistent with this perspective.
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1146. Mr. Justice G.H. Guttal Former Judge High Court of Bombay Flat No. 502 A. "Prachi" Versova Link Road P.K. Savant Marg ; Behind Amaltas, "HDFC Bank" Andheri West ; , Mumbai-400053 1147. Dr. A.B. Handa Chartered Engineer 21, Vardhaman Nagar, Drive-in Road, Navrangpura Ahmedabad-380009 1148. Mr. B.P. Handa Retd. Chief Engineer H P, PWD ; 76 1, Jawahar Nagar Mandi-171005 1149. Mr. D.N. Handa Ex-Engineer-in-Chief HP, PWD HIM Technarch, Seri Bazar Mandi Town-175001 1150. Mr. Justice T R Handa 3, Khullar Farm, Sultanpur, Mehrauli New Delhi-110030 1151. Mr. T.C. Handa B-2, Yogeshwar Park Society Makerpura Road, Near Bhavans's School Vadodara-390009 1152. Mr. C.L. Handu Consultant Engineer Contract Management ; # 201, GH-17, Sector-20, Panchkula-134112 1153. Mr. Vellalar R Hango Managing Director M S SPIM Engineering Pvt. Ltd. 24, Highways Colony Subramanipuram Trichy-620020 1154. Mr. R.L. Hans Engineer Member Retd. ; 403, Double Storey, New Rjinder Nagar New Delhi-110060 and dextroamphetamine.
18. References 1. Inoue A, Yanagisawa M, Kimura S, et al. The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc Natl Acad Sci USA 1989; 86: 28632867. Yanagisawa M, Kurihara H, Kimura S, et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988; 332: 411415. Advenier C, Sarria B, Naline E, Puybasset L, Lagente V. Contractile activity of three endothelins ET-1, ET-2 and ET-3 ; on the human isolated bronchus. Br J Pharmacol 1990; 100: 168172. Payne AN, Whittle BJR. Potent cyclo-oxygenase-mediated bronchoconstrictor effects of endothelin in the guinea-pig in vivo. Eur J Pharmacol 1990; 158: 303304. Lagente V, Chabrier PE, Mencia-Huerta J-M, Braquet P. Pharmacological modulation of the bronchopulmonary action of the vasoactive peptide, endothelin, administered by aerosol in the guinea-pig. Biochem Biophys Res Commun 1989; 158: 625632. Shimura S, Ishihara H, Satoh M, et al. Endothelin regulation of mucus glycoprotein secretion from feline tracheal submucosal glands. J Physiol 1992; 262: L208 L213. Haller H, Schaberg T, Lindschau C, Lode H, Distler A. Endothelin increases [Ca2 + ]i, protein phosphorylation, and O2 production in human alveolar macrophages. J Physiol 1991; 261: L478484. Uchida Y, Ninomiya H, Sakamoto T, et al. ET-1 released histamine from guinea-pig pulmonary but not peritoneal mast cells. Biochem Biophys Res Commun 1992; 189: 11961201. Filep JG, Fournier A, Fldes-Filep E. Acute proinflammatory actions of endothelin-1 in the guinea-pig lung: involvement of ETA and ETB receptors. Br J Pharmacol 1995; 115: 227236. Takuwa N, Takuwa Y, Yanagisawa M, Yamashita K, 19 and dionex.
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AIM: To examine the portal hemodynamics of gastric fundal varices GV ; without gastro-renal shunt GRS ; , and to retrospectively investigate the effects of various kinds of treatment on eradication. METHODS: Ninety-four liver cirrhosis patients at highrisk of GV were treated in our hospital and enrolled in this study. We retrospectively examined their characteristics, liver function, and portal hemodynamics of GV. We performed balloon-occluded retrograde transvenous obliteration BRTO ; at first. If it was not technically possible to perform BRTO, endoscopic injection sclerotherapy using -cyanoacrylate glue CA ; or percutaneous transhepatic obliteration PTO ; was performed. RESULTS: Among the 94 patients, a GRS was present in 79 84.0% ; , and absent in the remaining 15 16.0% ; . The subphrenic vein was connected to the inferior vena cava as the drainage vein in 13 86.7% ; out of the 15 cases without GRS. We performed BRTO in 6 patients, CA in 4 patients and PTO in 5 patients. The eradication rate was 100% for each procedure, but the rate of early recurrence within 6 mo was 16.7% for BRTO, 50.0% for CA and 40.0% for PTO, respectively. CONCLUSION: We should examine the hemodynamics before treatment of GV irrespective of the existence of GRS. If this hemodynamic examination reveals that the drainage vein connects directly to the inferior vena cava in GV without GRS, BRTO may be an effective treatment for GV with GRS.
Drug interactions: amphetamine decreased anorexic effect, may increase pyschotic symptoms benzphetamine decreased anorexic effect, may increase pyschotic symptoms bromocriptine the phenothiazine decreases the effect of bromocriptine dextroamphetamine decreased anorexic effect, may increase pyschotic symptoms dexfenfluramine decreased anorexic effect, may increase pyschotic symptoms diethylpropion decreased anorexic effect, may increase pyschotic symptoms fenfluramine decreased anorexic effect, may increase pyschotic symptoms guanethidine the agent decreases the effect of guanethidine mazindol decreased anorexic effect, may increase pyschotic symptoms methamphetamine decreased anorexic effect, may increase pyschotic symptoms metrizamide increased risk of convulsions phendimetrazine decreased anorexic effect, may increase pyschotic symptoms phenmetrazine decreased anorexic effect, may increase pyschotic symptoms phentermine decreased anorexic effect, may increase pyschotic symptoms phenylpropanolamine decreased anorexic effect, may increase pyschotic symptoms galantamine possible antagonism of action rivastigmine possible antagonism of action donepezil possible antagonism of action sparfloxacin increased risk of cardiotoxicity and arrhythmias terfenadine increased risk of cardiotoxicity and arrhythmias levofloxacin increased risk of cardiotoxicity and arrhythmias gatifloxacin increased risk of cardiotoxicity and arrhythmias grepafloxacin increased risk of cardiotoxicity and arrhythmias cisapride increased risk of cardiotoxicity and arrhythmias food interactions: not available generic name: promethazine synonyms: lilly 1516; isopromethazine; proazaimine; proazamine; promazinamide; promethazin; promethazine hcl; promethiazine; promezathine; prothazin; prothazine other brand names containing promethazine: allergan ; aprobit ; avomine ; dimapp ; diphergan ; diprazine ; diprozin ; dorme ; duplamin ; fargan ; fellozine ; fenazil ; fenergan ; fenetazina ; genphen ; hiberna ; histargan ; iergigan ; isophenergan ; lercigan ; lergigan ; mymethazine fortis ; phargan ; phenargan ; phencen ; phenergan ; phenergan fortis ; phensedyl ; pilpophen ; pipolphen ; procit ; prometasin ; prometazin ; prometh fortis ; prometh plain ; promethacon ; promethaine ; promethegan ; prorex ; protazine ; provigan ; pyrethia ; pyrethiazine ; remsed ; romergan ; synalgos ; tanidil ; thiergan ; valergine ; vallergine ; zipan-25 ; drug category: anti-allergic agents; antipruritics; phenothiazine derivatives drug type: small molecule; approved absorption: on average, 88% of a promethazine dose is absorbed after oral administration; however, the absolute bioavailability is only 25% because of first-pass clearance and dirithromycin.
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